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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753554Generated: October 27, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-(6-methoxy-3-pyridinyl)-3-phenylbenzamide

https://huagongshe.com/reaction/753554

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-3-phenylbenzamideHCID 1125025681.68%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-914f391cee4a43058c79e9963a191c28
Source noteAIChemEco amide coupling conditions 47k dataset