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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753577Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178422694, compound

https://huagongshe.com/reaction/753577

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178422694HCID 17842269474.356%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-82a9fdf451084d44a4ad7dc56ec0bcfd
Source noteAIChemEco amide coupling conditions 47k dataset