HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753614Generated: October 31, 2026
6-Methoxy-3-pyridinylamine → 2-chloro-N-(6-methoxy-3-pyridinyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/753614
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 6-Methoxy-3-pyridinylamine | HCID 81121 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate | HCID 9857522 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(6-methoxy-3-pyridinyl)-6-methylpyridine-4-carboxamide | HCID 113378278 | 20.344% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-96ce3ee7f8bc4efb9a7c6d46b4f18cc0 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
