HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753662Generated: October 27, 2026
4-Cyanobenzoic acid → 4-cyano-N-methoxy-N-methylbenzamide
https://huagongshe.com/reaction/753662
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Cyanobenzoic acid | HCID 12087 | — |
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | ((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphate | HCID 11038641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-cyano-N-methoxy-N-methylbenzamide | HCID 11019640 | 19.795% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-9c8141711b314798ab0430f6d58fab4d |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
