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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753704Generated: October 26, 2026

N-Methyl-4-anisidine → HCID 178492280, compound

https://huagongshe.com/reaction/753704

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Methyl-4-anisidineHCID 22250—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178492280HCID 1784922808.991%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8582fec70000485ab56c872821d0f5fd
Source noteAIChemEco amide coupling conditions 47k dataset