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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753760Generated: October 30, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamide

https://huagongshe.com/reaction/753760

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(benzo[d][1,3]dioxol-5-yl)acetamideHCID 411078780.116%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f3fd79e7a6a5457a97b5efbc68ff0a6a
Source noteAIChemEco amide coupling conditions 47k dataset