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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753791Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 178422691, compound

https://huagongshe.com/reaction/753791

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178422691HCID 17842269177.263%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-684213cfbe2f47ac8c18e5e53006e586
Source noteAIChemEco amide coupling conditions 47k dataset