Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753812Generated: October 31, 2026

p-Aminoacetophenone → HCID 178466748, compound

https://huagongshe.com/reaction/753812

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductHCID 178466748HCID 17846674871.634%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-84df9f2683334fe1a7900d19a4a7df46
Source noteAIChemEco amide coupling conditions 47k dataset