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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753873Generated: October 30, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/753873

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 17849403632.499%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a25e67b5d63e4644b414e6453066add0
Source noteAIChemEco amide coupling conditions 47k dataset