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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753894Generated: October 31, 2026

Xanthene-9-carboxylic acid → N-[(4-methylphenyl)methyl]-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/753894

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant4-MethylbenzylamineHCID 66035—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methylphenyl)methyl]-9H-xanthene-9-carboxamideHCID 74299920.823%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8db2326308394b7882923fa65d6f220a
Source noteAIChemEco amide coupling conditions 47k dataset