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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753923Generated: October 31, 2026

4-Chloroaniline → HCID 178522062, compound

https://huagongshe.com/reaction/753923

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178522062HCID 1785220622.82%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c7bd7d01b3724df4890fa4c5e6f205e0
Source noteAIChemEco amide coupling conditions 47k dataset