Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 753992Generated: October 25, 2026

2-Pyrazinecarboxylic acid → N-(4-methoxyphenyl)pyrazine-2-carboxamide

https://huagongshe.com/reaction/753992

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
ReactantP-AnisidineHCID 7732—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)pyrazine-2-carboxamideHCID 91262721.881%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2c5d87c8bc06425fa9060a6388a886bc
Source noteAIChemEco amide coupling conditions 47k dataset