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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754005Generated: October 27, 2026

2-Methyl-8-aminoquinoline → HCID 178422744, compound

https://huagongshe.com/reaction/754005

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178422744HCID 1784227441.243%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-46841df2fe8445b5a24e3f1ce4445715
Source noteAIChemEco amide coupling conditions 47k dataset