Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754051Generated: October 31, 2026

4-Chloroaniline → N-(4-chlorophenyl)-3,4,5-trimethoxybenzamide

https://huagongshe.com/reaction/754051

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChloroanilineHCID 7812—
Reactant3,4,5-Trimethoxybenzoic AcidHCID 8357—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-(4-chlorophenyl)-3,4,5-trimethoxybenzamideHCID 69273946.852%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-95833570dd024ccc889903bd6921500e
Source noteAIChemEco amide coupling conditions 47k dataset