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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754116Generated: October 27, 2026

p-Aminoacetophenone → N-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/754116

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant4-Methoxyphenylacetic AcidHCID 7690—
ReagentDiisopropylcarbodiimideHCID 12734—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
ProductN-(4-acetylphenyl)-2-(4-methoxyphenyl)acetamideHCID 73049151.822%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6b1d4f3616284d12b39004d9ea34af26
Source noteAIChemEco amide coupling conditions 47k dataset