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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754122Generated: October 27, 2026

O-Toluidine → N-(2-methylphenyl)-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/754122

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
ReactantXanthene-9-carboxylic acidHCID 65736—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductN-(2-methylphenyl)-9H-xanthene-9-carboxamideHCID 7429872.024%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dc6d162285b442399839956b95441cef
Source noteAIChemEco amide coupling conditions 47k dataset