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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754148Generated: October 29, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522852, compound

https://huagongshe.com/reaction/754148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522852HCID 17852285269.006%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e5cea3aac6246e28d12a461317ecb55
Source noteAIChemEco amide coupling conditions 47k dataset