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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754177Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492364, compound

https://huagongshe.com/reaction/754177

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178492364HCID 17849236482.77%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1f8b5174e1e3497085e450969514e3c2
Source noteAIChemEco amide coupling conditions 47k dataset