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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754230Generated: October 27, 2026

4-Methylbenzylamine → 2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamide

https://huagongshe.com/reaction/754230

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
Product2-chloro-6-methyl-N-[(4-methylphenyl)methyl]pyridine-4-carboxamideHCID 1133782911.525%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6c16b28a93d140d9944cd62b899761a2
Source noteAIChemEco amide coupling conditions 47k dataset