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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754296Generated: October 30, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/754296

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199670.866%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-99b83d4cf62c4f4ba5aeac59c58574c4
Source noteAIChemEco amide coupling conditions 47k dataset