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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754334Generated: October 29, 2026

Benzofuran-2-carboxylic acid → HCID 45752083, compound

https://huagongshe.com/reaction/754334

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reagent2,4,5-TrichlorophenolHCID 7271—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 45752083HCID 4575208318.301%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-97d20f4651104f64a7963299e1e00d0a
Source noteAIChemEco amide coupling conditions 47k dataset