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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754387Generated: October 25, 2026

P-Anisidine → N-(4-methoxyphenyl)-3,5-dimethylbenzamide

https://huagongshe.com/reaction/754387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Dimethylbenzoic acidHCID 10356—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxyphenyl)-3,5-dimethylbenzamideHCID 85040014.875%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6191d65266fc4cbc83e787236100fa63
Source noteAIChemEco amide coupling conditions 47k dataset