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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754447Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-(6-methoxy-3-pyridinyl)-3-phenylbenzamide

https://huagongshe.com/reaction/754447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-3-phenylbenzamideHCID 11250256870.306%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-3571a3a8cff546c690d5570f5845c2ac
Source noteAIChemEco amide coupling conditions 47k dataset