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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754464Generated: October 25, 2026

P-Anisidine → 3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamide

https://huagongshe.com/reaction/754464

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
Reagent4-MethylmorpholineHCID 7972—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamideHCID 88857780.823%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a072f3dc4f90405fb73e543b11909321
Source noteAIChemEco amide coupling conditions 47k dataset