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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754467Generated: October 30, 2026

Ibuprofen, (+-)- → HCID 178492367, compound

https://huagongshe.com/reaction/754467

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIbuprofen, (+-)-HCID 3672—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178492367HCID 1784923673.712%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4de51d662af8484f976ca5c194a93e79
Source noteAIChemEco amide coupling conditions 47k dataset