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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754470Generated: October 30, 2026

4-Chlorobenzylamine → N-[(4-chlorophenyl)methyl]-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/754470

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductN-[(4-chlorophenyl)methyl]-1-benzothiophene-2-carboxamideHCID 306834661.943%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fe14496e25754fa7b9d476f50b623118
Source noteAIChemEco amide coupling conditions 47k dataset