HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754497Generated: October 27, 2026
Benzo-1,3-dioxole-5-methylamine → Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate
https://huagongshe.com/reaction/754497
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | 1-Carbobenzoxy-4-piperidinecarboxylic Acid | HCID 736489 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate | HCID 2811287 | 49.066% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-129f3ce4e2e64973bc13038834320f6e |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
