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HRID75451

反应详情

EQUATION

反应方程式

HRID 75451 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2ccc(N)cc2)OC1(C)C
HCID2734620

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

C12H18BNO2

结构：FC(F)(F)c1cc(N2CC3CCC(C2)O3)nc(Cl)n1
HCID86665901

未命名化合物

PRODUCTS

生成物

1
结构：Nc1ccc(-c2nc(N3CC4CCC(C3)O4)cc(C(F)(F)F)n2)cc1
HCID66750236

未命名化合物

收率 86%

PROCEDURE

实验过程

The title compound was prepared in 86% yield from 3-(2-chloro-6-trifluoromethyl-pyrimidin-4-yl)-8-oxa-3-aza-bicyclo[3.2.1]octane (63) and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, using the general procedure from scheme 2 for the preparation of 6. MS (ES+): 351.2 (M+H)+.

WORKUP

后处理

  1. customfor the preparation of 6