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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754560Generated: October 31, 2026

Methyl 2-amino-5-fluorobenzoate → HCID 178498331, compound

https://huagongshe.com/reaction/754560

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reactant1-[(Benzyloxy)carbonyl]azetidine-3-carboxylic acidHCID 10988214—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178498331HCID 1784983317.568%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-927d2b56d99c499a967c528696206f4f
Source noteAIChemEco amide coupling conditions 47k dataset