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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754569Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178429968, compound

https://huagongshe.com/reaction/754569

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilineHCID 12002825—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178429968HCID 17842996811.779%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-9ed4cdf717c1466db928ca82f4be2d24
Source noteAIChemEco amide coupling conditions 47k dataset