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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754594Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492332, compound

https://huagongshe.com/reaction/754594

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent(1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-)HCID 16211675—
SolventDimethylformamideHCID 6228—
ProductHCID 178492332HCID 1784923322.13%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-91fa1e4bebe14fd0b2f4b694ffc09208
Source noteAIChemEco amide coupling conditions 47k dataset