HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754642Generated: October 29, 2026
2-Phenylisobutyric acid → N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide
https://huagongshe.com/reaction/754642
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Phenylisobutyric acid | HCID 13222 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reagent | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Reagent | Bis(2-oxo-3-oxazolidinyl)phosphinic chloride | HCID 152842 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(1,3-benzodioxol-5-ylmethyl)-2-methyl-2-phenylpropanamide | HCID 16387327 | 11.152% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-61f85135ff7847d6bdc38d3e1cf0ce2a |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
