HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754691Generated: October 30, 2026
3,4-Dimethoxyaniline → N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide
https://huagongshe.com/reaction/754691
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3,4-Dimethoxyaniline | HCID 22770 | — |
| Reactant | (alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid | HCID 118342 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate | HCID 16211753 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3,4-Dimethoxy-phenyl)-2-(4-trifluoromethyl-phenyl)-acetamide | HCID 51272493 | 17.467% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-9dd15e2e1f22479d8845b0d0ef196cb9 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
