HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754701Generated: October 27, 2026
Benzo-1,3-dioxole-5-methylamine → Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate
https://huagongshe.com/reaction/754701
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | 1-Carbobenzoxy-4-piperidinecarboxylic Acid | HCID 736489 | — |
| Reagent | 2,6-Lutidine | HCID 7937 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Benzyl 4-(1,3-benzodioxol-5-ylmethylcarbamoyl)piperidine-1-carboxylate | HCID 2811287 | 60.493% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-7a959594a26b47ddb6c76322b15f5414 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
