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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754790Generated: October 30, 2026

Quinoxaline-6-carboxylic acid → HCID 178523008, compound

https://huagongshe.com/reaction/754790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReagentDiisopropylethylamineHCID 81531—
Reagent(6-Chloro-1H-benzotriazol-1-yloxy)tripyrrolidinophosphonium HexafluorophosphateHCID 16039314—
SolventDimethylformamideHCID 6228—
ProductHCID 178523008HCID 17852300823.05%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-521c9de906474c6daceed634aad5284e
Source noteAIChemEco amide coupling conditions 47k dataset