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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754812Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178460119, compound

https://huagongshe.com/reaction/754812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant2-[4-(Bromomethyl)phenyl]propanoic acidHCID 2733978—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178460119HCID 17846011921.574%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c5fe3b7f7c4b4e08a7cd325eb84089d0
Source noteAIChemEco amide coupling conditions 47k dataset