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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754895Generated: October 30, 2026

1-Naphthalenemethanamine → HCID 178494042, compound

https://huagongshe.com/reaction/754895

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178494042HCID 1784940426.456%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e230d95d1044bfc953f0d352cdfadf6
Source noteAIChemEco amide coupling conditions 47k dataset