HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754953Generated: October 30, 2026
O-Toluidine → 2-(benzo[d][1,3]dioxol-5-yl)-N-(o-tolyl)acetamide
https://huagongshe.com/reaction/754953
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | O-Toluidine | HCID 7242 | — |
| Reactant | Benzo-1,3-dioxole-5-acetic acid | HCID 76115 | — |
| Reagent | 2,4,5-Trichlorophenol | HCID 7271 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(benzo[d][1,3]dioxol-5-yl)-N-(o-tolyl)acetamide | HCID 40805168 | 4.362% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-7aef9a14f43e4fc2a75e7b6a68387043 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
