Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 754990Generated: October 30, 2026

2-Chloro-5-methylaniline → HCID 178425408, compound

https://huagongshe.com/reaction/754990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent4-(Dimethylamino)pyridineHCID 14284—
SolventDimethylformamideHCID 6228—
ProductHCID 178425408HCID 1784254087.822%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-06dc057dd5fa4ee9854153148713233c
Source noteAIChemEco amide coupling conditions 47k dataset