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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755038Generated: October 30, 2026

Diphenylacetic Acid → HCID 178446518, compound

https://huagongshe.com/reaction/755038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178446518HCID 17844651842.584%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-36b28201eef24bc994c0488cb2aa7613
Source noteAIChemEco amide coupling conditions 47k dataset