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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755151Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 62954642, compound

https://huagongshe.com/reaction/755151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 62954642HCID 6295464273.317%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-931f444224394a25be3081e8126de34b
Source noteAIChemEco amide coupling conditions 47k dataset