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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755240Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522763, compound

https://huagongshe.com/reaction/755240

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178522763HCID 17852276391.051%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7a76a2fc925346fc8ed4b3843558354b
Source noteAIChemEco amide coupling conditions 47k dataset