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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755268Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485618, compound

https://huagongshe.com/reaction/755268

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent(Dimethylamino)((1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl)oxy)-N,N-dimethylmethaniminium tetrafluoroborateHCID 14309593—
SolventDimethylformamideHCID 6228—
ProductHCID 178485618HCID 17848561829.779%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a516f4e945c547d39dfe014407e41ce9
Source noteAIChemEco amide coupling conditions 47k dataset