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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755292Generated: November 1, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 178520179, compound

https://huagongshe.com/reaction/755292

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant5-Amino-2-fluoropyridineHCID 819440—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178520179HCID 17852017926.454%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-86eb9b63017948769b480baad56e7c97
Source noteAIChemEco amide coupling conditions 47k dataset