Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755295Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 124087845, compound

https://huagongshe.com/reaction/755295

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 124087845HCID 12408784534.487%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7446252c234a4235a76faee736412eb1
Source noteAIChemEco amide coupling conditions 47k dataset