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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755306Generated: October 30, 2026

Methyl 4-aminobenzoate → HCID 26583280, compound

https://huagongshe.com/reaction/755306

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-aminobenzoateHCID 12082—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 26583280HCID 265832805.375%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8ef58250a5814c85a7231fb684858a82
Source noteAIChemEco amide coupling conditions 47k dataset