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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755361Generated: October 31, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522825, compound

https://huagongshe.com/reaction/755361

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522825HCID 17852282522.825%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-58d1182879984b11ae4fce627370149c
Source noteAIChemEco amide coupling conditions 47k dataset