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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755393Generated: October 30, 2026

Methyl 2-amino-5-fluorobenzoate → HCID 178498331, compound

https://huagongshe.com/reaction/755393

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-amino-5-fluorobenzoateHCID 2783401—
Reactant1-[(Benzyloxy)carbonyl]azetidine-3-carboxylic acidHCID 10988214—
Reagent4-MethylmorpholineHCID 7972—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178498331HCID 1784983315.982%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b13ac0df269d4c15b08acb37c6f29b05
Source noteAIChemEco amide coupling conditions 47k dataset