HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bicyclo(2.2.1)hept-5-ene-2-carbonyl chloride → N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bicyclo(2.2.1)hept-5-ene-2-carbonyl chloride | HCID 98233 | — |
| Reactant | 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one | HCID 135594067 | — |
| Product | N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]bicyclo[2.2.1]hept-5-ene-2-carboxamide | HCID 135752647 | — |
Reaction Steps
In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 120 mg (0.74 mmol) bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087605B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-f76a8a8b48e24cfcac66d166cb5a1dec |
| Source note | uspto-grants-2006_08 |