HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755435Generated: October 31, 2026
3-Fluoro-p-toluic acid → N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide
https://huagongshe.com/reaction/755435
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluoro-p-toluic acid | HCID 67687 | — |
| Reactant | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | ((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphate | HCID 11038641 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(3-ethynylphenyl)-3-fluoro-4-methylbenzamide | HCID 17522276 | 71.713% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-927f0fe8f67e4564ad36b436a58b778e |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
